Paediatric Subgroup of the Clinical Transfusion and Haemovigilance Working Parties


To promote best practice, safe transfusion and blood conservation for neonates and children, through advocacy, educational resources and international collaboration.

Substantial variability in practice exists in clinical transfusion, patient blood management and blood conservation in paediatrics. Neonates and children are frequently transfused patient populations, yet they are relatively under-represented in clinical trials and the evidence-base to guide practice is limited. A number of clinical practices are extrapolated from the results of adult studies. Yet neonates and children have unique pathophysiology, specific vulnerabilities and different risk profiles compared to adult transfusion recipients. A disproportionate number of transfusion adverse events are reported in the neonatal and paediatric age groups. Any adverse outcome related to transfusion is particularly important in these young recipients, as most are anticipated to live for many years post transfusion. Transfusion decision making in paediatrics needs to consider the potential risks and benefits of a transfusion and any alternatives to transfusion.


The Paediatrics subgroup of the Clinical Transfusion and Haemovigilance working parties of ISBT is an international group of professionals with an interest in neonatal and paediatric transfusion medicine and transfusion safety. Our objectives are to develop educational tools and resources, create a network that promotes the sharing knowledge, research and ideas, as well as act as a forum for discussion. 


We meet at the biannual ISBT congress and hold regular teleconferences (2-3 times per year).

Joining the WP

To join the Paediatric Subgroup of the Clinical Transfusion and Haemovigilance working parties, you must be a member of either the Clinical Transfusion Working Party or the Haemovigilance Working Party. Working party members with an interest in neonatal or paediatric transfusion medicine or neonatal or paediatric transfusion safety and haemovigilance can apply to join the subgroup. We are keen to encourage members from a broad range of disciplines including scientific, nursing, clinical haematology, paediatrics, neonatology and transfusion medicine. 

Interested in joining the Paediatric Subgroup of the Clinical Transfusion and Haemovigilance working parties? Please email our Chairperson here



Some of the content is only accessible for ISBT-members.
To join us, click here.

Paeds meeting in Toronto

Lani Lieberman, Nancy Robitaille, Simon Stanworth, Helen New
Clare O’Reilly, Sarita Joshi (iPad - Gemma Crighton), Amy Kier

Paeds speakers in Toronto

Phil Spinella, Helen New and Ruchika Goel

Paediatric Haemovigilance Publications

  1. Analysis of pediatric adverse reactions to transfusions Vossoughi S, Perez G, Whitaker BI, Fung MK, Stotler B Transfusion, 2018, Jan; 58 (1): 60 – 69
  2. Transfusion reactions in pediatric compared with adult patients: a look at rate, reaction type, and associated products Oakley FD, Woods M, Arnold S, Young PP Transfusion, 2015 Marl 55 (3): 560 – 570
  3. Provider trends in paediatric and adult transfusion reaction reporting Vossoughi S, Parker- Jones S, Schwartz J, Stotler B Vox Sanguinis, 2019 Apr; 114 (3): 232 – 236
  4. Transfusion-associated circulatory overload in a pediatric intensive care unit: different incidences with different diagnostic criteria De Cloedt L, Emeriaud G, Lefebvre E, Kleiber N, Robitaille N, Jarlot C, Lacroix J, Gauvin F Transfusion, 2018 Apr; 58 (4): 1037 – 1044


Gemma Crighton

Gemma Crighton


Royal Children’s Hospital